Low dose naltrexone (LDN) therapy

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At standard doses (50 mg to 100 mg), naltrexone is used as an opioid antagonist to help treat alcohol and opioid dependence. However, at low doses (1 mg to 6 mg), LDN has been shown to increase endorphins, thereby reducing pain, and modulate the immune system to help stimulate and restore normal immune functions while also reducing inflammation. Due to its mechanism of action, LDN is commonly prescribed as an adjunct in a pain regimen or to help with autoimmune diseases. The immunomodulation and analgesia effects have not been seen at the higher, standard doses of therapy.

Custom Prescriptions is able to make LDN in several forms: capsules, liquid, sublingual drops and as a topical cream.

The starting dose can vary from 0.5 mg to 1.5 mg and is typically titrated to a dose of 4.5 mg, however, some patients may experience relief prior to reaching 4.5 mg.

Some of the conditions that LDN has been prescribed for includes:

  • Celiac disease
  • Chronic fatigue syndrome
  • Complex regional pain syndrome
  • Crohn’s disease
  • Fibromyalgia
  • Inflammatory Bowel Disease
  • Migraine
  • Multiple sclerosis
  • Peripheral neuropathy
  • Rheumatoid arthritis
  • Psoriasis
  • Ulcerative colitis

If you have any additional questions, please call us at 610-933-0920.